Protein flexibility, not disorder, is intrinsic to molecular recognition
نویسندگان
چکیده
منابع مشابه
Protein flexibility, not disorder, is intrinsic to molecular recognition
An 'intrinsically disordered protein' (IDP) is assumed to be unfolded in the cell and perform its biological function in that state. We contend that most intrinsically disordered proteins are in fact proteins waiting for a partner (PWPs), parts of a multi-component complex that do not fold correctly in the absence of other components. Flexibility, not disorder, is an intrinsic property of prote...
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ژورنال
عنوان ژورنال: F1000 Biology Reports
سال: 2013
ISSN: 1757-594X
DOI: 10.3410/b5-02